III. Role of allotransplantation for non-Hodgkin lymphoma and chronic lymphocytic leukemia

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III. Role of allotransplantation for non-Hodgkin lymphoma and chronic lymphocytic leukemia

With an incidence rate of 15 per 100 000, non-Hodgkin’s lymphoma (NHL) accounts for the majority of lymphoid neoplasms in Europe [1]. Although in most of these entities the results of first-line therapy are becoming more and more effective, allogeneic stem cell transplantation (alloSCT) is increasingly used in NHL. Numbers of NHL allotransplants registered with the European Society for Blood an...

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Hodgkin lymphoma transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma.

Transformation to a large cell lymphoma may occur during the course of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) in approximately 5% of the cases. This is known as Richter's transformation. A much less frequent transformation to Hodgkin lymphoma may occur. We report a case of CLL/SLL in which a transformation to Hodgkin lymphoma occurred, and we review previously publish...

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Allotransplantation for chronic lymphocytic leukemia.

Efforts to develop curative treatment strategies for chronic lymphocytic leukemia (CLL) in recent years have focused on allogeneic stem cell transplantation (alloSCT). The crucial anti-leukemic principle of alloSCT in CLL appears to be the immune-mediated anti-host activities conferred with the graft (graft-versus-leukemia effects, GVL). Evidence for GVL in CLL is provided by studies analyzing ...

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Hodgkin Lymphoma and Anaplastic Variants of Non-Hodgkin Lymphoma

  Background and Objectives: Classic Hodgkin lymphoma (CHL), anaplastic large cell lymphoma (ALCL) and some cases of diffuse large B cell lymphoma (DLBCL) have overlapping morphologic features. Since they all represent distinct clinico-pathologic entities, we explored the differential diagnostic impact of immunophenotyping to discriminate between them. Materials and Methods:...

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Evaluation of neuropathy during intensive vincristine chemotherapy for non-Hodgkin\'s lymphoma and Acute Lymphoblastic Leukemia

Back ground: Vincristine (VCR), is a chemotherapy drug, useful in the treatment of leukemia, lymphoma and solid tumor and it is a potent neurotoxin and sensory neuropathy drug which a common behavioral toxicity of this drug. Neuropathy is common squeal of intensive chemotherapy protocols that contain vincristine and corticosteroids. Materials and Methods: This study was a retrospective and ...

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ژورنال

عنوان ژورنال: Annals of Oncology

سال: 2011

ISSN: 0923-7534

DOI: 10.1093/annonc/mdr169